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mRNA: Therapeutics and Global Markets

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  • ARCTURUS THERAPEUTICS INC.
  • ASTRAZENECA
  • BIOCINA
  • BIONTECH SE
  • CUREVAC SE
  • ETHRIS GMBH
  • GENNOVA BIOPHARMACEUTICALS LTD.
  • GSK PLC.
  • IMMORNA(HANGZHOU) BIOTECHNOLOGY CO. LTD.
  • MERCK & CO. INC.
  • MODERNA INC.
  • NUTCRACKER THERAPEUTICS INC.
  • PFIZER INC.
  • PROVIDENCE THERAPEUTICS
  • SANOFI
  • STRAND THERAPEUTICS INC.
LSH 25.09.24

The global market for mRNA therapeutics was valued at $7.71 billion in 2025 and is forecast to remain stable or slightly decline to $7.69 billion by the end of 2030, at a compound annual growth rate (CAGR) of -0.04% during the forecast period of 2025 to 2030.

The global market for COVID mRNA therapeutics was valued at $7.65 billion in 2025 and is forecast to slightly decline to $7.58 billion by the end of 2030, at a CAGR of -0.2% during the forecast period of 2025 to 2030.

The global market for non-COVID diseases mRNA therapeutics was valued at $61.7 million in 2025 and is forecast to reach $118.9 million by the end of 2030, at a CAGR of 14% during the forecast period of 2025 to 2030.

Report Scope

The report analyzes the global market for mRNA therapeutics. It includes global revenue ($ millions) for the base year of 2024, estimated data for 2025 and projected compound annual growth rates (CAGRs) through 2030. The report examines the different types of mRNA and their applications for therapeutic use. It also focuses on mRNA patents and clinical trials and examines the trends affecting the market during the forecast period. The report profiles the leading companies and their strategic alliances and partnerships. The report segments the global market into North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW).

Report Includes

  • 19 data tables and 71 additional tables
  • An overview and analysis of the global markets for messenger RNA (mRNA)-based therapeutics
  • Analyses of the global market trends, with revenue data from 2022 to 2024, estimates for 2025, and projected CAGRs through 2030
  • Estimates of the size and revenue prospects for the global mRNA market, along with a market share analysis by disease type, indication, and region
  • Facts and figures pertaining to market dynamics, opportunities and deterrents, technological advances, regulations and the impacts of macroeconomic variables
  • Insights derived from Porter's Five Forces model, global supply chain and PESTLE analyses
  • Patent analysis, featuring key granted and published patents
  • Overview of the sustainability trends and ESG developments in the industry, with emphasis on the ESG practices followed by leading companies, their ESG ratings and consumer attitudes
  • Analysis of the industry structure, including companies' market shares and rankings, strategic alliances, M&A activity and a venture funding outlook
  • Profiles of the leading companies, including Moderna Inc., Pfizer Inc., BioNTech SE, Merck & Co., and Sanofi

Table of Contents

Chapter 1 Executive Summary

  • Market Outlook
  • Scope of Report
  • Market Summary
  • Market Growth Factors
  • Emerging Technologies
  • COVID mRNA Vaccines
  • Regional Analysis
  • Conclusion

Chapter 2 Market Overview

  • Technology Background
  • Evolution of RNA Therapeutics
  • DNA Therapeutics vs. RNA Therapeutics
  • RNA Therapeutics
  • mRNA as Therapeutics
  • Regulatory Agency-Approved mRNA Vaccines
  • Porter's Five Forces Analysis
  • Potential for New Entrants
  • Bargaining Power of Suppliers
  • Bargaining Power of Buyers
  • Threat of Substitute Products or Services
  • Industry Competition
  • Impact of U.S. Tariffs on the mRNA Therapeutics Market
  • Conclusion

Chapter 3 Market Dynamics

  • Overview
  • Market Drivers
  • Rising Numbers of Pandemics and Epidemics
  • Awareness of the Need for Vaccinations
  • Investments in mRNA Therapeutics Research
  • Market Restraints
  • Limitations of mRNA Vaccines
  • Production and Logistical Hurdles
  • Market Opportunities
  • Personalized Cancer Vaccines
  • Potential of mRNA Drugs to Treat Various Diseases

Chapter 4 Regulatory Landscape

  • Regulatory Scenario
  • Overview of Regulatory Bodies
  • Guidelines and Standards for mRNA Vaccines
  • Preclinical and Clinical Evaluation
  • Manufacturing and Post-Marketing Surveillance
  • Continual Monitoring and Risk Management

Chapter 5 Pipeline and Clinical Trial Analysis

  • Takeaways
  • mRNA Vaccines

Chapter 6 Market Segmentation Analysis

  • Segmentation Breakdown
  • Market Breakdown by Disease Type
  • Takeaways
  • COVID mRNA Vaccines
  • Non-COVID mRNA Vaccines and Therapeutics
  • Market Breakdown by Indication
  • Cancer
  • Infectious Diseases
  • Rare Diseases
  • Others
  • Geographic Breakdown
  • Market Breakdown, by Region
  • Takeaways
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World

Chapter 7 Emerging Technologies and Developments

  • Emerging Technologies in mRNA Therapeutics
  • Nanoparticles
  • Modified mRNA
  • Automated mRNA Synthesis Kits
  • Bio Platforms
  • Artificial Intelligence
  • AI Developments at mRNA Therapeutics Companies

Chapter 8 Patent Analysis

  • Takeaways
  • mRNA Publications
  • List of Patents

Chapter 9 Sustainability in the mRNA Therapeutics Industry: An ESG Perspective

  • Sustainability in the mRNA Therapeutics Industry
  • ESG Risk Ratings
  • ESG Performance Analysis
  • Environmental Performance
  • Social Performance
  • Governance Performance
  • Concluding Remarks from BCC Research

Chapter 10 Competitive Intelligence

  • Takeaways
  • Leading Companies in the mRNA Therapeutics Market, 2024
  • Strategic Analysis
  • Collaborations and Partnerships
  • Regulatory Approvals
  • Clinical Trials Data
  • Funding and Grants

Chapter 11 Appendix

  • Methodology
  • Abbreviations
  • Sources
  • Company Profiles
  • ARCTURUS THERAPEUTICS INC.
  • ASTRAZENECA
  • BIOCINA
  • BIONTECH SE
  • CUREVAC SE
  • ETHRIS GMBH
  • GENNOVA BIOPHARMACEUTICALS LTD.
  • GSK PLC.
  • IMMORNA (HANGZHOU) BIOTECHNOLOGY CO. LTD.
  • MERCK & CO. INC.
  • MODERNA INC.
  • NUTCRACKER THERAPEUTICS INC.
  • PFIZER INC.
  • PROVIDENCE THERAPEUTICS
  • SANOFI
  • STRAND THERAPEUTICS INC.
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