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시장보고서
상품코드
2117964
2형 당뇨병 : 시장 인사이트, 역학 및 시장 예측(2036년)Type 2 Diabetes - Market Insight, Epidemiology, and Market Forecast - 2036 |
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DelveInsight
주요 7개국 2형 당뇨병(T2DM) 시장 규모 및 전망
본 T2DM 시장 보고서는 표준 치료, 임상 실무 및 진화하는 치료 알고리즘을 포함한 현재 시장 상황에 대한 종합적인 분석을 제공합니다. T2DM 환자의 부담 동향, 매출 및 시장 점유율 동향, 피크 시 환자 점유율 및 치료법 보급 현황 분석을 평가하여, 전 세계 시장 규모에 대한 상세한 평가와 성장률 예측(과거 데이터 및 2022-2036년 예측)을 제시합니다. 본 보고서는 2형 당뇨병(T2DM) 분야의 주요 미충족 요구 사항을 부각시키고, 경쟁 구도 및 임상 상황을 정리함으로써 고부가가치 성장 기회를 밝혀내고, 향후 시장 성장 가능성에 대한 명확한 전망을 제시합니다.
2형 당뇨병(T2DM) 유병률 증가
2형 당뇨병(T2DM) 유병률의 증가는 T2DM 시장 확대의 주요 촉진요인입니다. 이는 비만율 상승, 앉아 있는 생활 습관, 고령화, 질병에 대한 인식 및 진단 향상, 혈당 조절 효과는 물론, 체중 관리, 심혈관계 및 신장에 유익한 효과를 가져오는 새로운 치료법의 채택 확대에 의해 뒷받침되고 있습니다.
신규 2형 당뇨병 치료법에서의 기회 확대
2형 당뇨병 분야에서 해결되지 않은 주요 요구 사항은 혈당 조절 개선, 지속적인 체중 감량 지원, 심혈관 및 신장 관련 합병증 완화, 그리고 치료 순응도 향상을 목표로 하는 차세대 치료법, 경구용 치료제, 그리고 다중 표적 대사 접근법에 대한 기회를 창출하고 있으며, 이를 통해 기존의 2형 당뇨병 치료법에 수반되는 한계를 해결하고 있습니다.
2형 당뇨병(T2DM)의 개요 및 진단
2형 당뇨병(T2DM)은 인슐린 저항성과 인슐린 분비 부족을 특징으로 하는 만성적이고 진행성인 대사 장애로, 그 결과 혈당 수치가 지속적으로 상승하고 미세혈관 및 대혈관 합병증의 위험이 높아집니다. 일반적으로 성인기에 발병하지만, 소아, 사춘기, 젊은 성인에서의 진단도 증가하는 추세입니다. 주요 위험 요인으로는 과체중이나 비만, 운동 부족, 노화, 당뇨병 가족력, 그리고 특정 대사 이상이 포함됩니다. 장기적인 관리에는 생활 습관 개선, 혈당 강하 요법 및 정기적인 모니터링이 포함되며, 이를 통해 혈당 조절을 달성하고 심혈관, 신장, 망막 및 신경 장애와 같은 합병증의 위험을 줄입니다.
2형 당뇨병(T2DM)은 특징적인 증상을 보이는 환자에 대해 HbA1c, 공복 혈장 포도당, 경구 포도당 부하 검사 또는 임의 혈장 포도당 검사 등의 혈당 검사를 통해 진단됩니다. 진단은 확립된 임상 기준에 따라 이루어지며, 명백한 고혈당이 확인되지 않는 경우에는 비정상적인 결과를 확인하기 위해 일반적으로 재검사가 실시됩니다. 종합적인 질환 관리 및 치료 계획을 지원하기 위해 지질 프로파일, 신기능, 혈압 및 당뇨병 관련 합병증 선별 검사 등의 추가 평가가 이루어질 수 있습니다.
2형 당뇨병(T2DM)의 치료
2형 당뇨병(T2DM) 치료의 주요 목표는 혈당 조절의 달성 및 유지, 당뇨병 관련 합병증 위험 감소, 건강한 체중 관리 지원, 그리고 장기적인 삶의 질 향상입니다. 현재의 관리 방법에는 생활 습관 개선과 혈당 강하 요법이 포함되며, 세마글루타이드(OZEMPIC, RYBELSUS), 틸제파티드(MOUNJARO),엠파글리플로진(JARDIANCE), 다파글리플로진(FARXIGA), 시타글립틴(JANUVIA), 인슐린 등의 약물이 질환 관리의 다양한 단계에서 널리 사용되고 있습니다. 경구 대사약, 차세대 인크레틴계 치료제, 그리고 레타톨티드,카글리세마, 서보두티드 등의 다중 수용체 작용제를 포함한 새로운 치료법은 혈당 조절 향상, 체중 감소 촉진, 더 광범위한 심혈관 및 신장에 대한 유익한 효과를 가져오는 것을 목표로 하는 동시에, 치료의 편의성과 복약 순응도 향상도 도모하고 있습니다.
2형 당뇨병(T2DM)의 역학적 분석 및 예측에 관한 주요 조사 결과
2형 당뇨병(T2DM)의 치료 상황은 생활 습관 개선, 혈당 모니터링, 약물 요법, 그리고 특정 환자를 대상으로 한 대사 수술을 아우르는 환자 중심의 다각적인 접근 방식으로 진화하고 있습니다. 건강한 식단, 규칙적인 신체 활동, 체중 관리 등의 생활 습관 개입은 여전히 치료의 기반을 이루고 있지만, 2형 당뇨병 유병률의 증가와 지속적인 혈당 조절에 대한 필요성 증대가 약물 요법에 대한 수요를 계속해서 견인하고 있습니다. 메트포르민은 여전히 널리 사용되는 1차 선택 약물이지만, 설포닐우레아계 약물, 글리니드계 약물, 티아졸리딘디온계 약물, DPP-4 억제제, SGLT2 억제제,GLP-1 수용체 작용제, 그리고 인슐린은 혈당 조절의 필요성, 동반 질환, 안전성, 그리고 환자의 희망에 따라 사용되고 있습니다. 시장은 혈당 강하 작용을 넘어서는 효과, 특히 심혈관 및 신장 보호, 체중 감소를 가져오는 치료법으로 점점 더 이동하고 있으며, 이는 SGLT2 억제제와 GLP-1 수용체 작용제의 지속적인 보급을 뒷받침하고 있습니다. 새롭게 등장하고 있는 병용요법 및 멀티 작용제 요법은 혈당 조절과 대사 결과 모두를 목표로함으로써 경쟁을 더욱 심화시킬 것으로 예상됩니다. 인슐린은 비인슐린 요법에도 불구하고 혈당 조절이 불충분한 환자에게 여전히 중요한 치료 선택지인 반면, 지속 혈당 모니터링 및 기타 디지털 도구는 보다 개인화된 치료 최적화를 지원하고 있습니다. 또한, 비만이나 혈당 조절이 불충분한 2형 당뇨병 적격 환자에게는 대사 수술도 확립된 선택지가 되고 있습니다. 전반적으로 2형 당뇨병 시장은 질병 부담의 증가, 치료의 강화, 심혈관 및 대사 효과를 동반하는 치료법에 대한 수요, 그리고 병용요법 및 차세대 치료법에서의 지속적인 혁신에 의해 형성될 것으로 예상됩니다.
전반적으로 메트포르민, SGLT2 억제제 및 GLP-1 수용체 작용제는 2형 당뇨병(T2DM) 관리의 핵심 축으로 자리 잡고 있지만, 이중 및 다중 표적 대사 요법이 혁신을 주도하고 있습니다. 새로운 병용요법과 차세대 인크레틴 계열 약물의 등장으로 인해, 혈당 조절, 체중 관리, 심혈관 및 신장 예후, 그리고 기존의 혈당 강하 요법을 넘어서는 기타 미충족 의료 수요를 충족시킴으로써 치료 선택지가 확대되고, 2형 당뇨병(T2DM) 시장을 재편할 가능성이 있다고 여겨집니다.
Type 2 Diabetes Mellitus (T2DM) Market Size and Forecast in the 7MM
DelveInsight's 'Type 2 Diabetes Mellitus (T2DM) - Market Insights, Epidemiology and Market Forecast - 2036' report delivers an in-depth understanding of the T2DM, historical and forecasted epidemiology, as well as the T2DM market trends in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.
The T2DM market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates, T2DM patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment, and growth rate projections (Historical & Forecast 2022-2036) across global regions. The report highlights key unmet medical needs in T2DM and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.
Key Factors Driving the Type 2 Diabetes Mellitus (T2DM) Market
Rising T2DM Prevalence
The increasing prevalence of T2DM is a key driver of T2DM market expansion, supported by rising obesity rates, sedentary lifestyles, aging populations, increasing disease awareness and diagnosis, and growing adoption of newer therapies that provide effective glycemic control alongside weight-management, cardiovascular, and kidney benefits.
Rising Opportunities in Novel T2DM Therapies
The substantial unmet need in T2DM is creating opportunities for next-generation therapies, oral treatment options, and multi-target metabolic approaches aimed at improving glycemic control, supporting sustained weight loss, reducing cardiovascular and kidney-related complications, and enhancing treatment adherence, thereby addressing limitations associated with conventional T2DM therapies.
Type 2 Diabetes Mellitus (T2DM) Overview and Diagnosis
T2DM is a chronic, progressive metabolic disorder characterized by insulin resistance and inadequate insulin secretion, resulting in persistently elevated blood glucose levels and an increased risk of microvascular and macrovascular complications. It commonly develops in adulthood but is increasingly diagnosed in children, adolescents, and younger adults. Major risk factors include overweight or obesity, physical inactivity, advancing age, family history of diabetes, and certain metabolic conditions. Long-term management involves lifestyle modification, glucose-lowering therapies, and regular monitoring to achieve glycemic control and reduce the risk of cardiovascular, kidney, retinal, and neuropathic complications.
T2DM is diagnosed through blood glucose testing, including HbA1c, fasting plasma glucose, oral glucose tolerance testing, or random plasma glucose testing in patients with characteristic symptoms. Diagnosis is based on established clinical criteria, with repeat testing generally used to confirm abnormal results in the absence of unequivocal hyperglycemia. Additional assessments may include lipid profile, kidney function, blood pressure, and screening for diabetes-related complications to support comprehensive disease management and treatment planning.
Type 2 Diabetes Mellitus (T2DM) Treatment
The primary goals of T2DM treatment are to achieve and maintain glycemic control, reduce the risk of diabetes-related complications, support healthy weight management, and improve long-term quality of life. Current management includes lifestyle modifications and glucose-lowering therapies, with agents such as semaglutide (OZEMPIC, RYBELSUS), tirzepatide (MOUNJARO), empagliflozin (JARDIANCE), dapagliflozin (FARXIGA), sitagliptin (JANUVIA), and insulin widely used across different stages of disease management. Emerging therapies, including oral metabolic agents, next-generation incretin-based therapies, and multi-receptor agonists such as retatrutide, CagriSema, and survodutide, aim to enhance glycemic control, promote weight loss, and provide broader cardiovascular and kidney benefits while improving treatment convenience and adherence.
Type 2 Diabetes Mellitus (T2DM) Unmet Needs
The section "unmet needs of T2DM" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.
Key Findings from Type 2 Diabetes Mellitus (T2DM) Epidemiological Analysis and Forecast
Type 2 Diabetes Mellitus (T2DM) Drug Chapters & Competitive Analysis
The T2DM drug chapter provides a detailed, market-focused review of approved therapies and the emerging pipeline across Phase I-III clinical trials. It covers the mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, and strategic partnerships for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the T2DM treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the T2DM therapeutics market.
Approved Therapies for Type 2 Diabetes Mellitus (T2DM)
Bexagliflozin (BRENZAVVY): TheracosBio
It is a SGLT2 inhibitor approved by the US FDA in January 2023 as an adjunct to diet and exercise to improve glycemic control in adults with T2DM. By inhibiting SGLT2 in the renal proximal tubule, it reduces glucose reabsorption and lowers the renal threshold for glucose, leading to increased urinary glucose excretion and improved blood sugar control. BRENZAVVY is administered orally. It also stands out as the lowest priced SGLT2 inhibitor currently available in the US market.
Semaglutide (OZEMPIC/RYBELSUS/WEGOVY): Novo Nordisk
Semaglutide is a GLP-1 receptor agonist marketed by Novo Nordisk under different brand names with distinct FDA-approved indications.
OZEMPIC: Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is also indicated to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease, and to reduce the risk of sustained eGFR decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease.
RYBELSUS: Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is also indicated to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes who are at high risk for these events.
Type 2 Diabetes Mellitus (T2DM) Pipeline Analysis
CagriSema: Novo Nordisk
CagriSema, developed by Novo Nordisk, is a once-weekly subcutaneous fixed-dose combination of the long-acting amylin analogue cagrilintide (2.4 mg) and the GLP-1 receptor agonist semaglutide (2.4 mg). It is being investigated for the treatment of adults with type 2 diabetes mellitus (T2DM), with the potential to improve glycemic control and provide additional benefits in body weight and cardiometabolic risk factors.
Survodutide (BI 456906): Boehringer Ingelheim
Survodutide (BI 456906), developed by Boehringer Ingelheim, is a glucagon receptor (GCGR)/GLP-1 receptor dual agonist being evaluated for T2DM. By targeting both receptors, survodutide is designed to enhance glucose control while also supporting weight reduction and broader metabolic improvements. The compound is currently in Phase III development.
Type 2 Diabetes Mellitus (T2DM) Key Players, Market Leaders and Emerging Companies
Type 2 Diabetes Mellitus (T2DM) Drug Updates
Drug Class Insights
The T2DM treatment landscape is evolving toward a patient-centered, multifaceted approach encompassing lifestyle modification, glucose monitoring, pharmacotherapy, and, in selected patients, metabolic surgery. Lifestyle interventions, including healthy diet, regular physical activity, and weight management, remain the foundation of care; however, the growing prevalence of T2DM and increasing need for durable glycemic control continue to drive demand for pharmacologic therapies. Metformin remains a widely used first-line option, while sulfonylureas, glinides, thiazolidinediones, DPP-4 inhibitors, SGLT2 inhibitors, GLP-1 receptor agonists, and insulin are utilized based on glycemic needs, comorbidities, safety, and patient preferences. The market is increasingly shifting toward therapies that provide benefits beyond glucose lowering, particularly cardiovascular and renal protection and weight reduction, supporting continued uptake of SGLT2 inhibitors and GLP-1 receptor agonists. Emerging combination and multi-agonist therapies are expected to further intensify competition by targeting both glycemic control and metabolic outcomes. Insulin remains an important treatment option for patients with inadequate control despite non-insulin therapies, while continuous glucose monitoring and other digital tools are supporting more personalized treatment optimization. Metabolic surgery also represents an established option for eligible patients with obesity and poorly controlled T2DM. Overall, the T2DM market is expected to be shaped by rising disease burden, increasing treatment intensification, demand for therapies with cardiometabolic benefits, and continued innovation in combination and next-generation therapies.
Drug Class/Insights into Leading Emerging and Marketed Therapies in Type 2 Diabetes Mellitus (T2DM) (2022-2036 Forecast)
The T2DM treatment landscape comprises therapies targeting multiple pathways involved in glucose regulation, insulin sensitivity, renal glucose handling, and metabolic control. Established therapies include biguanides, sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, thiazolidinediones, GLP-1 receptor agonists, and insulin, while emerging therapies increasingly focus on multi-target mechanisms and improved cardiometabolic outcomes.
Overall, metformin, SGLT2 inhibitors, and GLP-1 receptor-based therapies remain key pillars of T2DM management, while dual- and multi-target metabolic therapies are driving innovation. The emergence of novel combination therapies and next-generation incretin-based agents is expected to broaden treatment options and potentially reshape the T2DM market by addressing glycemic control, weight management, cardiovascular and renal outcomes, and other persistent unmet needs beyond conventional glucose lowering.
Type 2 Diabetes Mellitus (T2DM) Drug Uptake
This section focuses on the uptake rate of potential drugs expected to be launched in the market during the forecast period (2026-2036). The analysis covers the T2DM market's uptake by drugs, patient uptake by therapy, and sales of each drug.
Type 2 Diabetes Mellitus (T2DM) Therapies Price Scenario & Trends
Pricing and analogue assessment of T2DM therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.
Industry Experts and Physician Views for Type 2 Diabetes Mellitus (T2DM)
To keep up with T2DM market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry experts were contacted for insights on the T2DM emerging therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns in T2DM, including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.
DelveInsight's analysts connected with 10+ KOLs to gather insights; however, interviews were conducted with 6+ KOLs in the 7MM. Centers such as the University of Mississippi Medical Center, University of Bologna, and Teikyo University School of Medicine, etc. were contacted. Their opinion helps understand and validate current and emerging T2DM therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for market access, therapy adoption, and pipeline prioritization in T2DM.
Qualitative Analysis: SWOT and Conjoint Analysis
We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and conjoint analysis.
In the SWOT analysis of T2DM, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided.
Conjoint analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.
The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.
Market Insights