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비만 : 시장 인사이트, 역학 및 시장 예측(2036년)

Obesity - Market Insight, Epidemiology, and Market Forecast - 2036

발행일: | 리서치사: 구분자 DelveInsight | 페이지 정보: 영문 200 Pages | 배송안내 : 2-10일 (영업일 기준)

    
    
    




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비만에 대한 인사이트 및 동향

  • DelveInsight의 분석에 따르면, 2025년 주요 시장(미국, EU 4개국(독일, 프랑스, 이탈리아, 스페인), 영국 및 일본)의 비만 관련 시장 규모는 약 160억 달러였습니다.
  • 2025년, 주요 7개국에서 비만 환자 총수는 약 1억 9,000만 명이었습니다. 주요 7개국 중 미국이 가장 많은 환자 수를 차지했습니다.
  • 2025년 미국의 비만 시장 총 규모는 약 130억 달러였으나, 비만으로 인한 부담 증가와 장기적인 약물 치료가 필요한 만성 질환으로서의 비만에 대한 인식 제고를 배경으로 2036년까지 성장할 것으로 예상됩니다.
  • 비만 치료 시장은 노보 노르디스크(Novo Nordisk)와 일라이 릴리(Eli Lilly)를 중심으로 고도로 집중되어 있으며, 두 회사의 인크레틴 계열 치료제가 유효성 및 상업적 성과에 대한 벤치마크가 되고 있습니다. 노보 노르디스크의 ‘SAXENDA(릴라글루티드)’ 및 ‘WEGOVY(세마글루티드)’, 그리고 일라이 릴리의 ‘ZEPBOUND(틸제파티드)’는 여전히 약물 치료 시장의 주요 축을 이루고 있습니다. 두 회사는 또한 차세대 경구용 제제 및 다중 작용제 요법의 개발을 추진하고 있으며, 이는 편의성이 더 높고 잠재적으로 더 효과적인 치료 옵션으로의 전환이 진행되고 있음을 반영합니다.
  • 비만 치료 파이프라인은 확립된 GLP-1 요법의 범위를 넘어 빠르게 진화하고 있으며, 체중 감량 효과의 크기, 지속성 및 편의성을 향상시키는 것을 목표로 하는 임상시험 단계의 후보 약물이 점점 더 늘어나고 있습니다. RGT-075(레골 테라퓨틱스)나 에니세파타이드(CT-388; Roche/Carmot Therapeutics)와 같은 새로운 후보 약물은 다양한 차세대 접근 방식을 구현하고 있습니다. 이러한 프로그램들은 전반적으로 치료 선택의 폭을 넓히고, 현재의 인크레틴 요법에 수반되는 과제를 해결하며, 비만 치료 시장 전체의 경쟁을 심화시킬 가능성이 있습니다.
  • 2025년 12월, 노보 노르디스크는 체중 관리를 목적으로 한 최초의 경구용 GLP-1 수용체 작용제인 경구용 세마글루타이드 25mg(WEGOVY)이 FDA 승인을 획득했다고 발표했습니다. 그 후, 이 회사는 메디케어 파트 D 및 ‘Bridge’ 프로그램을 통해 접근성을 확대했으며, 영국과 UAE에서의 국제적인 출시, 그리고 EU에서의 승인이 이 제품의 급속한 보급을 뒷받침했습니다.
  • 영국에서는 출시 3주 만에 약 30만 명의 환자가 WEGOVY 정제를 사용하고 있는 것으로 추정되며, 이는 단순히 주사제에서 경구제로의 전환에 그치지 않고, 비만 치료를 받는 환자층을 확대할 가능성을 시사합니다.
  • 비만 관리에서 중요한 미충족 의료 수요 중 하나는 더 오래 지속되는 치료법의 개발입니다. 향후 10년 동안 혁신적인 치료법이 시장에 등장할 전망이지만, 투여 빈도가 낮은 약물을 개발한다는 점에서 제약 기업에게는 여전히 큰 기회가 남아 있습니다. 현재 투여 빈도가 가장 낮은 치료법이라 하더라도 주 1회 주사가 필요하며, 이는 많은 환자에게 장벽이 될 수 있습니다.

비만 시장의 규모 및 전망

  • 2025년 주요 7개국(G7)의 비만 시장 규모 : 약 160억 달러
  • 비만 시장 성장률(2022-2036년) : 연평균 성장률(CAGR) 약 27%

본 비만 시장 보고서는 표준 치료, 임상 실무, 진화하는 치료 알고리즘 등 현재의 치료 상황에 대한 종합적인 분석을 제공합니다. 비만 환자의 부담 동향, 매출 및 시장 점유율 동향, 피크 시 환자 점유율 및 치료 도입 현황 분석을 평가함과 동시에, 주요 7개국 지역 전체에 걸친 상세한 시장 규모 평가 및 성장률 예측(과거 데이터 및 2022-2036년 예측)을 제시하고 있습니다. 본 보고서는 비만 분야의 주요 미충족 요구에 초점을 맞추고, 경쟁 구도 및 임상 환경을 분석하여 고부가가치 성장 기회를 규명하는 한편, 향후 시장 성장 가능성에 대한 명확한 전망을 제시하고 있습니다.

대상 지역:

북미 : 미국

유럽 : 독일, 프랑스, 이탈리아, 스페인, 영국

아시아태평양 : 일본

비만의 이해 및 치료 알고리즘

비만의 개요 및 진단

비만은 건강을 해칠 가능성이 있는 과도한 지방 축적을 특징으로 하는 만성적이고 복잡한 질환입니다. 비만은 2형 당뇨병이나 심장병의 위험을 높이는 원인이 됩니다. 또한 뼈 건강과 생식 기능에 영향을 미치며, 특정 암의 위험도 높입니다. 과체중이나 비만은 에너지 섭취(식사)와 에너지 소비(신체 활동)의 불균형으로 인해 발생합니다. 대부분의 경우, 비만은 비만을 유발하는 환경적, 심리사회적 요인 및 유전적 변이에 의한 다인자성 질환입니다. 일부 환자의 경우, 약물, 질환 또는 유전성 증후군과 같은 단일한 주요 원인이 확인되기도 합니다.

과체중 및 비만의 진단은 체중과 신장을 측정하고 체질량 지수(BMI: 체중(kg)/신장2(m2))를 산출하여 이루어집니다. 체질량 지수는 체지방량의 대체 지표이며, 허리 둘레와 같은 추가 측정값도 비만 진단에 도움이 됩니다. 비만을 정의하기 위한 BMI 분류는 영아, 소아 및 청소년의 경우 연령과 성별에 따라 다릅니다.

현재 비만 치료의 현황

효과적인 치료 전략에는 생활 습관 개선, 약물 요법, 그리고 체중 감량 수술이 포함됩니다. 생활 습관 개선을 통해 최대 10%의 체중 감소를 기대할 수 있지만, 중증 비만으로 고통받는 많은 환자에게는 불충분한 경우도 있습니다. 따라서 약물 요법이나 체중 감량 수술은, 특히 비만과 관련된 합병증을 완화하기 위해 상당한 체중 감량이 필요한 경우, 생활 습관 개입을 보완하는 중요한 수단이 됩니다. 약물 요법의 선택지는 수년까지 확대되어 왔으며, 글루카곤 유사 펩타이드-1(GLP-1) 수용체 작용제, GLP-1과 포도당 의존성 인슐린 분비 촉진 폴리펩티드 수용체(GIPR)를 모두 표적으로 하는 이중 작용제,췌장 리파제 억제제, 교감신경 자극제 등이 포함됩니다. 또한, 교감신경 자극제와 항경련제의 병용요법이나, 오피오이드 수용체 길항제와 도파민/노르아드레날린 재흡수 억제제의 병용요법 등, 병용요법은 비만의 다면적인 특성에 대처하기 위한 다양한 작용기전을 제공합니다.

비만 치료 시장은 기존의 생활 습관 개입이나 구세대 약물 요법에서 매우 효과적인 인크레틴 계열 치료법으로의 전환을 배경으로, 대폭적인 다각화 단계에 접어들고 있습니다. 현재 노보노르디스크와 일라이 릴리가 주도적인 위치를 차지하고 있으며, 노보노르디스크의 세마글루티드(WEGOVY) 및 릴라글루티드(SAXENDA),그리고 일라이 릴리의 틸제파티드(ZEPBOUND)가 브랜드 비만 치료제 시장의 주요 구성요소를 이루고 있습니다.

비만의 역학

비만의 역학적 분석 및 예측을 통한 주요 인사이트

  • DelveInsight의 분석에 따르면, 2025년에는 주요 7개국 전체 비만 유병 사례의 약 60%를 미국이 차지할 것으로 예상되며, 이는 미국 내 비만의 질병 부담이 크다는 점을 반영함과 동시에, 평가 대상 지역 중 미국이 최대 시장임을 보여줍니다.
  • 2025년, 미국에서는 5-19세 아동 약 700만 명이 비만을 앓고 있으며, 이는 아동의 질병 부담이 크다는 점과 청소년을 대상으로 한 효과적인 예방 및 치료 전략에 대한 수요가 높아지고 있음을 여실히 보여줍니다.
  • EU4 국가 및 영국 중에서 2025년 비만 유병자 수가 가장 많았던 나라는 독일로, 약 1,800만 명이었습니다. 이 막대한 환자 수는 독일이 비만 관리 분야의 주요 시장임을 여실히 보여주며, 효과적인 약물 요법의 도입에 있어 큰 잠재력을 지니고 있습니다.
  • 일본에서는 질환에 대한 인식 제고와 치료 선택지의 확대를 배경으로, 치료를 받고 있는 비만 환자 수가 서서히 증가하고 있습니다. 2025년 시점에서 일본에서는 성인 환자 약 15만 명, 소아 환자 약 180명이 치료를 받고 있었습니다. 진단, 치료 이용, 약물 요법에 대한 접근성이 개선됨에 따라, 치료 대상자의 지속적인 증가가 비만 치료제에 대한 수요의 추가 확대를 뒷받침할 것으로 예상됩니다.

비만 시장의 전망

비만 치료 시장의 전망은 매우 효과적인 인크레틴 계열 치료법의 채택 확대와 파이프라인 내 지속적인 혁신에 힘입어 계속해서 매우 밝습니다. 세마글루타이드(WEGOVY)와 틸제파티드(ZEPBOUND)는 현저한 체중 감량 효과와 적응증 확장에 힘입어 계속해서 시장의 주요 리더로서의 지위를 유지할 것으로 예상됩니다. 오를리스타트(XENICAL)나 펜터민/토피라메이트(QSYMIA)와 같은 기존 치료법은 특정 환자 집단에서 계속해서 일정한 역할을 할 것으로 예상됩니다. 한편, 신흥 치료법은 경쟁을 더욱 격화시키고 치료 선택지를 확대함으로써 비만 시장의 지속적인 성장을 뒷받침할 것입니다.

  • 2025년, 미국의 비만 치료 시장 규모는 약 130억 달러였습니다. 이 수치는 신흥 치료제의 도입에 따라 대폭 확대될 것으로 예상됩니다.
  • 2025년 EU4 및 영국의 시장 규모는 25억 달러 이상으로 추정됩니다.
  • EU4 및 영국 중에서 2025년에는 독일이 약 7억 2,000만 달러로 가장 큰 시장 점유율을 차지했습니다.
  • 2025년, 일본의 비만 치료 시장 총 규모는 약 7,000만 달러였으며, 예측 기간(2026-2036년)에 걸쳐 확대될 것으로 전망됩니다.

약제 분류별/비만 치료 분야의 주요 신흥 치료법에 대한 분석(2022-2036년 예측)

비만 치료 분야에는 저분자 화합물, 펩타이드, 재조합 DNA 치료법, 단일클론 항체, GLP-1 수용체 작용제, 이중/다중 수용체 인크레틴 작용제 및 병용요법이 포함되며, 유효성, 내약성, 투여 편의성이 점점 더 중요시되고 있습니다. 저분자 화합물은 경구 투여의 편의성과 확립된 작용기전으로 인해 여전히 중요하지만, 펩타이드 및 재조합 DNA 기반 치료법이 새로운 인크레틴 치료 분야를 주도하고 있습니다. 단일클론 항체 및 기타 생물학적 제제도 새로운 치료법으로 부상하고 있지만, 비만 치료에서 그 역할은 비교적 제한적입니다.

  • 저분자 화합물은 특히 식욕, 포만감, 영양소 흡수를 조절하는 중추 작용 및 위장관 작용을 통해 비만 치료에서 여전히 중요한 약물군입니다. 오를리스타트(XENICAL)나 펜터민과 같은 확립된 치료법이 이 접근법의 좋은 예이지만, 그 체중 감량 효과는 일반적으로 새로운 인크레틴 기반 치료법에 비해 미미합니다.
  • 경구용 GLP-1 요법,특히 올포르글리프론(FOUNDAYO)이나 경구용 세마글루티드(WEGOVY 정)의 등장으로, 경구 투여의 편의성과 인크레틴 계열 치료에 수반되는 높은 유효성이 결합됨에 따라, 비만 치료 시장에서 저분자 화합물의 중요성이 크게 높아질 것으로 기대됩니다.

자주 묻는 질문

  • 2025년 주요 7개국의 비만 시장 규모는 어떻게 되나요?
  • 2025년 미국의 비만 시장 규모는 얼마로 예상되나요?
  • 비만 시장의 연평균 성장률(CAGR)은 어떻게 되나요?
  • 비만 치료 시장에서 주요 기업은 어디인가요?
  • 비만 치료에 사용되는 주요 약물은 무엇인가요?
  • 비만 치료 시장의 향후 전망은 어떤가요?
  • 2025년 일본의 비만 치료 시장 규모는 어떻게 되나요?

목차

제1장 주요 인사이트

제2장 소개

제3장 주요 요약

제4장 주요 사건

제5장 역학 및 시장 예측 조사 방법

제6장 비만 : 시장 개요

제7장 질환 배경과 개요

제8장 역학 및 환자 인구

제9장 환자 경과

제10장 시판 치료제

제11장 새로운 치료법

제12장 비만 : 시장 분석

제13장 KOL의 견해

제14장 SWOT 분석

제15장 미충족 수요

제16장 시장 진입 및 보험 상환

제17장 부록

제18장 DelveInsight의 서비스 내용

제19장 면책사항

제20장 DelveInsight 소개

KSM 26.08.31

Obesity Insights and Trends

  • According to DelveInsight's analysis, obesity market size was nearly USD 16 billion in the leading markets (the United States, the EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan) in 2025.
  • In 2025, the total number of prevalent cases of obesity in the 7MM was approximately 190 million. Among the 7MM countries, the US accounted for the highest number of prevalent cases.
  • The total market size of obesity in the US in 2025 was approximately USD 13 billion, this is anticipated to grow by 2036, driven by the rising obesity burden, increasing recognition of obesity as a chronic disease requiring long-term pharmacological management.
  • The obesity treatment landscape is highly concentrated around Novo Nordisk and Eli Lilly, with their incretin-based therapies setting the benchmark for efficacy and commercial performance. SAXENDA (liraglutide) and WEGOVY (semaglutide) from Novo Nordisk, together with ZEPBOUND (tirzepatide) from Eli Lilly, remain key pillars of the pharmacological market. Both companies are also pursuing next-generation oral formulations and multi-agonist therapies, reflecting an ongoing shift toward more convenient and potentially more effective treatment options.
  • The obesity pipeline is rapidly evolving beyond established GLP-1 therapies, with a growing number of investigational assets designed to improve the magnitude, durability, and convenience of weight loss. Emerging candidates such as RGT-075 (Regor Therapeutics) and enicepatide (CT-388; Roche/Carmot Therapeutics) represent diverse next-generation approaches. Collectively, these programs could broaden the therapeutic landscape, address limitations associated with current incretin therapies, and intensify competition across the obesity market.
  • In December 2025, Novo Nordisk announced FDA approval of oral semaglutide 25 mg (WEGOVY) as the first oral GLP-1 receptor agonist for weight management. Novo subsequently expanded access through Medicare Part D and its Bridge program, while international launches in the UK and UAE and approval in the EU supported rapid adoption.
  • In the UK, approximately 300,000 patients were estimated to be using the WEGOVY pill within three weeks of launch, suggesting potential to expand the treated obesity population beyond a simple shift from injectable to oral therapy.
  • One critical unmet need in obesity management is the development of longer-acting therapies. While innovative treatments are expected to enter the market over the next decade, there remains a significant opportunity for pharmaceutical companies to advance drugs that require less frequent administration. Currently, even the lowest-frequency treatments necessitate weekly injections, which can be a barrier for many patients.

Obesity Market size and forecast

  • 2025 Obesity Market Size in the 7MM: ~USD 16 billion
  • Obesity Growth Rate (2022-2036): ~27% CAGR

DelveInsight's "Obesity- Market Insights, Epidemiology, and Market Forecast - 2036" report delivers an in-depth understanding of obesity, historical and forecasted epidemiology, as well as the OBESITY market trends in the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan.

The obesity market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates, obesity patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment and growth rate projections (Historical & Forecast 2022-2036) across the 7MM regions. The report highlights key unmet medical needs in obesity and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.

Geography Covered:

North America: The United States

Europe: Germany, France, Italy, Spain and the United Kingdom

Asia-Pacific: Japan

Obesity Understanding and Treatment Algorithm

Obesity Overview and Diagnosis

Obesity is a chronic complex disease defined by excessive fat deposits that can impair health. Obesity can lead to increased risk of type 2 diabetes and heart disease. It can affect bone health and reproduction, and it increases the risk of certain cancers. Overweight and obesity result from an imbalance of energy intake (diet) and energy expenditure (physical activity). In most cases, obesity is a multifactorial disease due to obesogenic environments, psycho-social factors, and genetic variants. In some patients, single major causes like medications, diseases, or genetic syndromes are identified.

The diagnosis of overweight and obesity is made by measuring people's weight and height and by calculating the Body Mass Index (BMI): weight (kg)/height2 (m2). The body mass index is a surrogate marker of fatness and additional measurements, such as the waist circumference, can help the diagnosis of obesity. The BMI categories for defining obesity vary by age and gender in infants, children, and adolescents.

Current Obesity Treatment Landscape

Effective therapeutic strategies include lifestyle modifications, pharmacotherapy, and bariatric surgery. Lifestyle changes can result in up to 10% weight reduction, though this may be insufficient for many patients dealing with severe obesity. Pharmacotherapy and bariatric surgery, therefore, represent critical adjuncts to lifestyle interventions, especially in cases where significant weight loss is required to mitigate obesity-related complications. Pharmacological options have expanded over the years and include Glucagon-like Peptide-1 (GLP-1) receptor agonists, dual agonists that target both GLP-1 and Glucose-dependent Insulinotropic Polypeptide Receptors (GIPR), pancreatic lipase inhibitors, and sympathomimetics. Additionally, combination therapies, such as sympathomimetic-anticonvulsant or opioid receptor antagonist-dopamine/noradrenaline reuptake inhibitors, offer diverse mechanisms of action to address the multifaceted nature of obesity.

The obesity market is entering a period of significant diversification, driven by a shift from traditional lifestyle interventions and earlier-generation pharmacotherapies toward highly effective incretin-based treatments. Novo Nordisk and Eli Lilly currently hold leading positions, with semaglutide (WEGOVY) and liraglutide (SAXENDA) from Novo Nordisk and tirzepatide (ZEPBOUND) from Eli Lilly forming key components of the branded obesity treatment landscape.

Obesity Unmet Needs

The section "unmet needs of obesity" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.

1. Need for longer-acting therapies

2. Demand for safer and more effective obesity medications

3. Limited access and reimbursement for obesity treatments

4. Need for updated treatment guidelines in obesity management and others...

Obesity Epidemiology

Key Findings from Obesity Epidemiological Analysis and Forecast

  • According to DelveInsight's analysis, the United States accounted for approximately 60% of the total prevalent obesity cases across the 7MM in 2025, reflecting its substantial disease burden and positioning the US as the largest market within the assessed geographies.
  • In 2025, approximately 7 million children aged 5-19 years in the US were living with obesity, underscoring the significant pediatric disease burden and the growing need for effective prevention and treatment strategies targeting younger populations.
  • Among the EU4 and the UK, Germany recorded the highest number of prevalent obesity cases in 2025, at approximately 18 million. The large affected population highlights Germany as a key market for obesity management and represents considerable potential for the adoption of effective pharmacological therapies.
  • Japan is witnessing a gradual increase in treated obesity cases, supported by growing disease awareness and the expanding availability of treatment options. In 2025, Japan had approximately 150,000 treated adult cases and around 180 treated pediatric cases. The continued increase in treated populations is expected to support greater demand for obesity therapies as diagnosis, treatment-seeking, and access to pharmacological interventions improve.

Obesity Drug Analysis & Competitive Landscape

The obesity drug chapter provides a detailed, market-focused review of approved therapies and the emerging pipeline across Phase I-III clinical trials. It covers mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, strategic partnerships upcoming key catalyst for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the obesity treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the obesity therapeutics market.

Approved Therapies for Obesity

Orforglipron (FOUNDAYO): Eli Lilly

Orforglipron (FOUNDAYO) is an oral, once-daily GLP-1 receptor agonist developed by Eli Lilly and approved by the US FDA, for use in combination with a reduced-calorie diet and increased physical activity to reduce excess body weight and maintain long-term weight reduction in adults with obesity or adults with overweight and at least one weight-related comorbidity. Orforglipron is administered orally with or without food, with an approved maximum dose of 17.2 mg once daily, and represents a new oral GLP-1 treatment option for chronic weight management.

  • In April 2026, Eli Lilly and Company announced that the US FDA approved FOUNDAYO for adults with obesity or overweight with weight-related comorbidities.

Obesity Pipeline Analysis

Enicepatide (CT-388): Roche/Carmot Therapeutics

Enicepatide (CT-388) is an investigational once-weekly subcutaneous dual GLP-1/GIP receptor agonist for obesity and associated comorbidities, including type 2 diabetes. It features biased signaling with minimal B-arrestin recruitment, supporting sustained receptor activity. CT-388 was designed to have potent activity on both the GLP-1 and GIP receptors but with minimal to no B-arrestin recruitment on either receptor. This biased signaling significantly minimizes receptor internalization and consequent desensitization, which is expected to lead to prolonged pharmacological activity.

Obesity Key Players, Market Leaders and Emerging Companies

  • Eli Lilly
  • Novo Nordisk
  • Currax Pharmaceuticals
  • Roche
  • Regor Therapeutics
  • D&D Pharmatech/Pfizer

And more

Obesity Drug Updates

  • In June 2026, Roche presented late-breaking Phase II data on enicepatide (CT-388) at the American Diabetes Association's 2026, demonstrating its efficacy and safety in individuals with overweight or obesity.
  • In April 2026, Eli Lilly and Company announced that FOUNDAYO is now available for adults with obesity or overweight and related comorbidities, following its US FDA approval on April 1, 2026.
  • In January 2025, Regor Therapeutics announced topline results from its Phase IIa clinical trial for RGT-075, a leading oral once-daily small molecule full agonist of GLP-1 receptor.

Obesity Market Outlook

The obesity market outlook remains highly positive, driven by the growing adoption of highly effective incretin-based therapies and continued pipeline innovation. Semaglutide (WEGOVY) and tirzepatide (ZEPBOUND) are expected to remain key market leaders, supported by substantial weight-loss efficacy and expanding indications. Established therapies such as orlistat (XENICAL), and phentermine/topiramate (QSYMIA) are likely to retain a role in specific patient populations. Meanwhile, emerging therapies could further intensify competition and expand treatment options, supporting sustained growth of the obesity market.

  • In 2025, the obesity market size in the US was around USD 13 billion. This figure is expected to grow significantly with the introduction of emerging therapies.
  • The total market size of EU4 and the UK was estimated to be more than USD 2.5 billion in 2025.
  • Among EU4 and the UK, Germany accounted for the highest market share with approximately USD 720 million in 2025.
  • In 2025, the total market size of obesity was approximately USD 70 million in Japan, which is anticipated to increase during the forecast period (2026-2036).

Drug Class/Insights into Leading Emerging Therapies in Obesity (2022-2036 Forecast)

The obesity treatment landscape includes small molecules, peptides, recombinant DNA therapies, monoclonal antibodies, GLP-1 receptor agonists, dual/multi-receptor incretin agonists, and combination therapies, with increasing emphasis on efficacy, tolerability, and convenient administration. Small molecules remain important due to their oral convenience and established mechanisms, while peptide and recombinant DNA-based therapies dominate the newer incretin landscape. Monoclonal antibodies and other biologic approaches represent additional emerging modalities, although their role in obesity remains comparatively limited.

  • Small molecules remain an important drug class in obesity treatment, particularly through centrally acting and gastrointestinal mechanisms that regulate appetite, satiety, and nutrient absorption. Established therapies such as orlistat (XENICAL) and phentermine exemplify this approach, although their weight-loss efficacy is generally more modest than that of newer incretin-based therapies.
  • The emergence of oral GLP-1 therapies, particularly orforglipron (FOUNDAYO) and the oral semaglutide (WEGOVY pill), is expected to significantly increase the importance of small molecules in the obesity market by combining the convenience of oral administration with the higher efficacy associated with incretin-based treatment.

Obesity Drug Uptake

This section focuses on the uptake rate of potential drugs expected to be launched in the market during the forecast period (2026-2036). The analysis covers the obesity drug's uptake, performance at peak, factors affecting performance during prime years of growth, patient uptake by therapy, and anticipated sales generated by each drug.

Following its US approval and launch, orforglipron (FOUNDAYO) is positioned for fast market uptake, with its once-daily oral formulation offering a potentially differentiated and more convenient alternative to other obesity therapies.

Detailed insights of emerging therapies' drug uptake is included in the report...

Market Access and Reimbursement of therapies in Obesity

The report further provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenario of therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.

As the obesity market transitions toward broader adoption and oral therapies, manufacturers are increasingly leveraging affordability programs to improve patient access. While Injectable WEGOVY continues to carry a US list price of approximately USD 1,349 per month, although commercial insurance and cash-pay programs can reduce patient costs to as low as USD 25 and USD 349 per month, respectively.

Lilly's ZEPBOUND is offered through its Self-Pay Journey Program at USD 299-449 per month depending on dose, despite list prices ranging from approximately USD 499 to USD 1,086 per month. Meanwhile, the newly launched oral WEGOVY and Lilly's oral GLP-1 therapy, orforglipron (FOUNDAYO), have entered the market with self-pay prices starting at USD 149 per month, with most higher-dose regimens priced between USD 299 and USD 349 per month, reflecting a broader industry push to improve accessibility as the obesity treatment landscape expands.

Reimbursement is a crucial factor that affects the drug's access to the market. Often, the decision to reimburse comes down to the price of the drug relative to the benefit it produces in treated patients. To reduce the healthcare burden of these high-cost therapies, many payment models are being considered by payers and other industry insiders.

NOTE: Further Details are provided in the final report.

Obesity Therapies Price Scenario & Trends

Pricing and analogue assessment of obesity therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.

Pricing of Obesity Approved Drugs

  • The estimated annual treatment cost of semaglutide (WEGOVY) in the US was approximately USD 12,505 in 2025, reflecting the substantial cost associated with long-term obesity management.

Industry Experts and Physician Views for Obesity

To keep up with obesity market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry Experts were contacted for insights on the obesity emerging therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns in obesity, including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.

DelveInsight's analysts connected with 10+ KOLs to gather insights at country level. Centers such as the Princeton Spine & Joint Center, University Hospital Giessen, and Saitama Medical University etc. were contacted.

Their opinion helps understand and validate current and emerging obesity therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for market access, therapy adoption, and pipeline prioritization in obesity.

Qualitative Analysis: SWOT and Attribute Analysis

We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and attribute analysis.

In the SWOT analysis of obesity, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provide attribute analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.

The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.

Scope of the Report:

  • The report covers a segment of key events, an executive summary, a descriptive overview of obesity, explaining their causes, signs and symptoms, pathogenesis, and currently available treatments.
  • Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression along treatment guidelines.
  • Additionally, an all-inclusive account of both the current and emerging treatments, along with the elaborative profiles of late-stage and prominent therapies, will have an impact on the current treatment landscape.
  • A detailed review of the obesity market, historical and forecasted market size, market share by therapies, detailed assumptions, and rationale behind our approach is included in the report, covering the 7MM drug outreach.
  • The report provides an edge while developing business strategies by understanding trends through SWOT analysis and expert insights/KOL views, patient journey, and treatment preferences that help in shaping and driving the 7MM obesity market.

Report Insights

  • Obesity Patient Population Forecast
  • Obesity Therapeutics Market Size
  • Obesity Pipeline Analysis
  • Obesity Market Size and Trends
  • Obesity Market Opportunity (Current and Forecasted)

Report Key Strengths

  • Epidemiology-based (Epi-based) Bottom-up Forecasting
  • Artificial Intelligence (AI) - enabled Market Research Report
  • 11-year forecast
  • Obesity Market Outlook (North America, Europe, Asia-Pacific)
  • Patient Burden Trends (by geography)
  • Obesity Treatment Addressable Market (TAM)
  • Obesity Competitive Landscape
  • Obesity Major Companies Insights
  • Obesity Price Trends and Analogue Assessment
  • Obesity Therapies Drug Adoption/Uptake
  • Obesity Therapies Peak Patient Share analysis

Report Assessment

  • Obesity Current Treatment Practices
  • Obesity Unmet Needs
  • Obesity Clinical Development Analysis
  • Obesity Emerging Drugs Product Profiles
  • Obesity Market Attractiveness
  • Obesity Qualitative Analysis (SWOT and Attribute analysis)

FAQs:

Market Insights

  • What was the obesity market size, the market size by therapies, market share (%) distribution in 2025, and what would it look like by 2036? What are the contributing factors for this growth?
  • What are the anticipated pricing variations among different geographies for the emerging therapies in the future?
  • What can be the future treatment paradigm of obesity?
  • What are the disease risks, burdens, and unmet needs of obesity? What will be the growth opportunities across the 7MM concerning the patient population with obesity?
  • Who is the major future competitor in the market, and how will the competitors affect their market share?
  • What are the current options for the treatment of obesity? What are the current guidelines for treating obesity in the US, Europe, and Japan?

Reasons to Buy:

  • The report will help in developing business strategies by understanding the latest trends and changing treatment dynamics driving the obesity market.
  • Bottom up forecasting builds from the affected population to product forecasts, delivering a robust, data driven approach ideal for new therapies and novel classes.
  • Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
  • Understand the existing market opportunities in varying geographies and the growth potential over the coming years.
  • Identifying strong upcoming players in the market will help devise strategies to help get ahead of competitors.
  • Detailed analysis, ranking of class-wise potential current, and emerging therapies under the attribute analysis section to provide visibility around leading classes.
  • To understand KOLs' perspectives on the accessibility, acceptability, and compliance-related challenges of existing treatment to overcome barriers in the future.
  • Detailed insights on the unmet needs of the existing market so that the upcoming players can strengthen their development and launch strategy.
  • This Artificial Intelligence (AI) enabled report summarize and simplify complex datasets with in the report into clear, actionable insights for stakeholders, investors, and healthcare providers, enabling faster, data driven decisions.

Table of Contents

1. Key Insights

2. Report Introduction

3. Executive Summary

4. Key Events

5. Epidemiology and Market Forecast Methodology

6. Obesity Market Overview at a Glance

  • 6.1. Market Share by Therapies (%) Distribution of Obesity in 2025 in the 7MM
  • 6.2. Market Share by Therapies (%) Distribution of Obesity in 2036 in the 7MM

7. Disease Background and Overview

  • 7.1. Introduction
  • 7.2. Signs and Symptoms
  • 7.3. Risk Factors and Causes
  • 7.4. Classification
  • 7.5. Pathophysiology
    • 7.5.1. Controlling Food Intake
    • 7.5.2. Dysregulation of Lipid and Glucose Metabolism
    • 7.5.3. Role of Adipocyte Inflammatory Secretagogues
  • 7.6. Clinical Manifestations
  • 7.7. Complications
  • 7.8. Diagnosis
    • 7.8.1. Diagnosis of Childhood Obesity
    • 7.8.2. Diagnosis of Adolescent Obesity
    • 7.8.3. Diagnosis of Morbid Obesity
    • 7.8.4. Diagnosis of Metabolic Syndrome
    • 7.8.5. Diagnostic Guidelines
    • 7.8.6. American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines for Diagnosis of Patients with Obesity
    • 7.8.7. Diagnostic Algorithm
  • 7.9. Treatment and Management
    • 7.9.1. Treatment and Management Guidelines
    • 7.9.2. The Endocrine Society Pharmacological Management of Obesity Guideline
    • 7.9.3. European Society of Endocrinology Clinical Practice Guideline
    • 7.9.4. The European Association for the Study of Obesity (EASO) Clinical Practice Guidelines
    • 7.9.5. American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines for Medical Care of Patients with Obesity
    • 7.9.6. Treatment Algorithms

8. Epidemiology and Patient Population

  • 8.1. Key Findings
  • 8.2. Assumptions and Rationale: 7MM
  • 8.3. Epidemiology Scenario
  • 8.4. Total Prevalent Cases of Obesity in the 7MM
  • 8.5. The United States
    • 8.5.1. Total Prevalent Cases of Obesity in the United States
    • 8.5.2. Total Treated Cases of Obesity in the United States
  • 8.6. EU4 and the UK
    • 8.6.1. Total Prevalent Cases of Obesity in EU4 and the UK
    • 8.6.2. Total Treated Cases of Obesity in EU4 and the UK
  • 8.7. Japan
    • 8.7.1. Total Prevalent Cases of Obesity in Japan
    • 8.7.2. Total Treated Cases of Obesity in Japan

9. Patient Journey

10. Marketed Therapies

  • 10.1. Competitive Landscape: Marketed Therapies
  • 10.2. Orforglipron (FOUNDAYO): Eli Lilly
    • 10.2.1. Product Description
    • 10.2.2. Regulatory Milestones
    • 10.2.3. Other Developmental Activities
    • 10.2.4. Clinical Development
    • 10.2.5. Safety and Efficacy
    • 10.2.6. Analyst Views
  • 10.3. Tirzepatide (ZEPBOUND): Eli Lilly
    • 10.3.1. Product Description
    • 10.3.2. Regulatory Milestones
    • 10.3.3. Other Development Activities
    • 10.3.4. Clinical Development
    • 10.3.5. Safety and Efficacy
    • 10.3.6. Analyst Views
  • 10.4. Semaglutide (WEGOVY): Novo Nordisk
    • 10.4.1. Product Description
    • 10.4.2. Regulatory Milestones
    • 10.4.3. Other Developmental Activities
    • 10.4.4. Clinical Development
    • 10.4.5. Safety and Efficacy
    • 10.4.6. Analyst Views

11. Emerging Therapies

  • 11.1. Competitive Landscape: Emerging Therapies
  • 11.2. Enicepatide (CT-388): Roche/Carmot Therapeutics
    • 11.2.1. Product Description
    • 11.2.2. Other Developmental Activities
    • 11.2.3. Clinical Developmental Activities
      • 11.2.3.1. Clinical Trial Information
    • 11.2.4. Safety and Efficacy
    • 11.2.5. Analyst View
  • 11.3. RGT-075: Regor Therapeutics
    • 11.3.1. Product Description
    • 11.3.2. Other Developmental Activities
    • 11.3.3. Clinical Developmental Activities
      • 11.3.3.1. Clinical Trial Information
    • 11.3.4. Safety and Efficacy
    • 11.3.5. Analyst View

12. Obesity: Market Analysis

  • 12.1. Key Findings
  • 12.2. Total Market Size of Obesity in the 7MM
  • 12.3. Market Outlook
  • 12.4. Key Market Forecast Assumptions
    • 12.4.1. Cost Assumptions and Rebates
    • 12.4.2. Pricing Trends
    • 12.4.3. Analogue Assessment
    • 12.4.4. Launch Year and Therapy Uptake
  • 12.5. Attribute Analysis
  • 12.6. United States Market Size
    • 12.6.1. Total Market Size of Obesity in the United States
    • 12.6.2. Market Size of Obesity by Therapies in the United States
  • 12.7. EU4 and the UK Market Size
    • 12.7.1. Total Market Size of Obesity in EU4 and the UK
    • 12.7.2. Market Size of Obesity by Therapies in EU4 and the UK
  • 12.8. Japan Market Size
    • 12.8.1. Total Market Size of Obesity in Japan
    • 12.8.2. Market Size of Japan by Therapies in Japan

13. KOL Views

14. SWOT Analysis

15. Unmet Needs

16. Market Access and Reimbursement

  • 16.1. The United States
    • 16.1.1. Centre for Medicare and Medicaid Services (CMS)
  • 16.2. EU4 and the UK
    • 16.2.1. Germany
    • 16.2.2. France
    • 16.2.3. Italy
    • 16.2.4. Spain
    • 16.2.5. United Kingdom
  • 16.3. Japan
    • 16.3.1. MHLW
  • 16.4. Market Access and Reimbursement for Obesity
    • 16.4.1. The United States
    • 16.4.2. EU4 and UK
    • 16.4.3. Japan

17. Appendix

  • 17.1. Bibliography
  • 17.2. Report Methodology

18. DelveInsight Capabilities

19. Disclaimer

20. About DelveInsight

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