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시장보고서
상품코드
2117965
비만 : 시장 인사이트, 역학 및 시장 예측(2036년)Obesity - Market Insight, Epidemiology, and Market Forecast - 2036 |
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DelveInsight
비만 시장의 규모 및 전망
본 비만 시장 보고서는 표준 치료, 임상 실무, 진화하는 치료 알고리즘 등 현재의 치료 상황에 대한 종합적인 분석을 제공합니다. 비만 환자의 부담 동향, 매출 및 시장 점유율 동향, 피크 시 환자 점유율 및 치료 도입 현황 분석을 평가함과 동시에, 주요 7개국 지역 전체에 걸친 상세한 시장 규모 평가 및 성장률 예측(과거 데이터 및 2022-2036년 예측)을 제시하고 있습니다. 본 보고서는 비만 분야의 주요 미충족 요구에 초점을 맞추고, 경쟁 구도 및 임상 환경을 분석하여 고부가가치 성장 기회를 규명하는 한편, 향후 시장 성장 가능성에 대한 명확한 전망을 제시하고 있습니다.
북미 : 미국
유럽 : 독일, 프랑스, 이탈리아, 스페인, 영국
아시아태평양 : 일본
비만의 개요 및 진단
비만은 건강을 해칠 가능성이 있는 과도한 지방 축적을 특징으로 하는 만성적이고 복잡한 질환입니다. 비만은 2형 당뇨병이나 심장병의 위험을 높이는 원인이 됩니다. 또한 뼈 건강과 생식 기능에 영향을 미치며, 특정 암의 위험도 높입니다. 과체중이나 비만은 에너지 섭취(식사)와 에너지 소비(신체 활동)의 불균형으로 인해 발생합니다. 대부분의 경우, 비만은 비만을 유발하는 환경적, 심리사회적 요인 및 유전적 변이에 의한 다인자성 질환입니다. 일부 환자의 경우, 약물, 질환 또는 유전성 증후군과 같은 단일한 주요 원인이 확인되기도 합니다.
과체중 및 비만의 진단은 체중과 신장을 측정하고 체질량 지수(BMI: 체중(kg)/신장2(m2))를 산출하여 이루어집니다. 체질량 지수는 체지방량의 대체 지표이며, 허리 둘레와 같은 추가 측정값도 비만 진단에 도움이 됩니다. 비만을 정의하기 위한 BMI 분류는 영아, 소아 및 청소년의 경우 연령과 성별에 따라 다릅니다.
현재 비만 치료의 현황
효과적인 치료 전략에는 생활 습관 개선, 약물 요법, 그리고 체중 감량 수술이 포함됩니다. 생활 습관 개선을 통해 최대 10%의 체중 감소를 기대할 수 있지만, 중증 비만으로 고통받는 많은 환자에게는 불충분한 경우도 있습니다. 따라서 약물 요법이나 체중 감량 수술은, 특히 비만과 관련된 합병증을 완화하기 위해 상당한 체중 감량이 필요한 경우, 생활 습관 개입을 보완하는 중요한 수단이 됩니다. 약물 요법의 선택지는 수년까지 확대되어 왔으며, 글루카곤 유사 펩타이드-1(GLP-1) 수용체 작용제, GLP-1과 포도당 의존성 인슐린 분비 촉진 폴리펩티드 수용체(GIPR)를 모두 표적으로 하는 이중 작용제,췌장 리파제 억제제, 교감신경 자극제 등이 포함됩니다. 또한, 교감신경 자극제와 항경련제의 병용요법이나, 오피오이드 수용체 길항제와 도파민/노르아드레날린 재흡수 억제제의 병용요법 등, 병용요법은 비만의 다면적인 특성에 대처하기 위한 다양한 작용기전을 제공합니다.
비만 치료 시장은 기존의 생활 습관 개입이나 구세대 약물 요법에서 매우 효과적인 인크레틴 계열 치료법으로의 전환을 배경으로, 대폭적인 다각화 단계에 접어들고 있습니다. 현재 노보노르디스크와 일라이 릴리가 주도적인 위치를 차지하고 있으며, 노보노르디스크의 세마글루티드(WEGOVY) 및 릴라글루티드(SAXENDA),그리고 일라이 릴리의 틸제파티드(ZEPBOUND)가 브랜드 비만 치료제 시장의 주요 구성요소를 이루고 있습니다.
비만의 역학적 분석 및 예측을 통한 주요 인사이트
비만 치료 시장의 전망은 매우 효과적인 인크레틴 계열 치료법의 채택 확대와 파이프라인 내 지속적인 혁신에 힘입어 계속해서 매우 밝습니다. 세마글루타이드(WEGOVY)와 틸제파티드(ZEPBOUND)는 현저한 체중 감량 효과와 적응증 확장에 힘입어 계속해서 시장의 주요 리더로서의 지위를 유지할 것으로 예상됩니다. 오를리스타트(XENICAL)나 펜터민/토피라메이트(QSYMIA)와 같은 기존 치료법은 특정 환자 집단에서 계속해서 일정한 역할을 할 것으로 예상됩니다. 한편, 신흥 치료법은 경쟁을 더욱 격화시키고 치료 선택지를 확대함으로써 비만 시장의 지속적인 성장을 뒷받침할 것입니다.
약제 분류별/비만 치료 분야의 주요 신흥 치료법에 대한 분석(2022-2036년 예측)
비만 치료 분야에는 저분자 화합물, 펩타이드, 재조합 DNA 치료법, 단일클론 항체, GLP-1 수용체 작용제, 이중/다중 수용체 인크레틴 작용제 및 병용요법이 포함되며, 유효성, 내약성, 투여 편의성이 점점 더 중요시되고 있습니다. 저분자 화합물은 경구 투여의 편의성과 확립된 작용기전으로 인해 여전히 중요하지만, 펩타이드 및 재조합 DNA 기반 치료법이 새로운 인크레틴 치료 분야를 주도하고 있습니다. 단일클론 항체 및 기타 생물학적 제제도 새로운 치료법으로 부상하고 있지만, 비만 치료에서 그 역할은 비교적 제한적입니다.
Obesity Market size and forecast
DelveInsight's "Obesity- Market Insights, Epidemiology, and Market Forecast - 2036" report delivers an in-depth understanding of obesity, historical and forecasted epidemiology, as well as the OBESITY market trends in the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan.
The obesity market report delivers a comprehensive analysis of the current treatment landscape, including standards of care, clinical practices, and evolving therapeutic algorithms. It evaluates, obesity patient burden trends, revenue & market share dynamics, peak patient share & therapy uptake analysis, and provides an in-depth market size assessment and growth rate projections (Historical & Forecast 2022-2036) across the 7MM regions. The report highlights key unmet medical needs in obesity and maps the competitive and clinical landscape to uncover high-value opportunities, providing a clear outlook on future market growth potential.
North America: The United States
Europe: Germany, France, Italy, Spain and the United Kingdom
Asia-Pacific: Japan
Obesity Overview and Diagnosis
Obesity is a chronic complex disease defined by excessive fat deposits that can impair health. Obesity can lead to increased risk of type 2 diabetes and heart disease. It can affect bone health and reproduction, and it increases the risk of certain cancers. Overweight and obesity result from an imbalance of energy intake (diet) and energy expenditure (physical activity). In most cases, obesity is a multifactorial disease due to obesogenic environments, psycho-social factors, and genetic variants. In some patients, single major causes like medications, diseases, or genetic syndromes are identified.
The diagnosis of overweight and obesity is made by measuring people's weight and height and by calculating the Body Mass Index (BMI): weight (kg)/height2 (m2). The body mass index is a surrogate marker of fatness and additional measurements, such as the waist circumference, can help the diagnosis of obesity. The BMI categories for defining obesity vary by age and gender in infants, children, and adolescents.
Current Obesity Treatment Landscape
Effective therapeutic strategies include lifestyle modifications, pharmacotherapy, and bariatric surgery. Lifestyle changes can result in up to 10% weight reduction, though this may be insufficient for many patients dealing with severe obesity. Pharmacotherapy and bariatric surgery, therefore, represent critical adjuncts to lifestyle interventions, especially in cases where significant weight loss is required to mitigate obesity-related complications. Pharmacological options have expanded over the years and include Glucagon-like Peptide-1 (GLP-1) receptor agonists, dual agonists that target both GLP-1 and Glucose-dependent Insulinotropic Polypeptide Receptors (GIPR), pancreatic lipase inhibitors, and sympathomimetics. Additionally, combination therapies, such as sympathomimetic-anticonvulsant or opioid receptor antagonist-dopamine/noradrenaline reuptake inhibitors, offer diverse mechanisms of action to address the multifaceted nature of obesity.
The obesity market is entering a period of significant diversification, driven by a shift from traditional lifestyle interventions and earlier-generation pharmacotherapies toward highly effective incretin-based treatments. Novo Nordisk and Eli Lilly currently hold leading positions, with semaglutide (WEGOVY) and liraglutide (SAXENDA) from Novo Nordisk and tirzepatide (ZEPBOUND) from Eli Lilly forming key components of the branded obesity treatment landscape.
Obesity Unmet Needs
The section "unmet needs of obesity" outlines the critical gaps between the current state of patient care, diagnosis, and the ideal & effective management of the disease. It highlights the obstacles experienced by patients, clinicians, and researchers and identifies potential solutions for future progress.
Key Findings from Obesity Epidemiological Analysis and Forecast
Obesity Drug Analysis & Competitive Landscape
The obesity drug chapter provides a detailed, market-focused review of approved therapies and the emerging pipeline across Phase I-III clinical trials. It covers mechanism of action, clinical trial data, regulatory approvals, patents, collaborations, strategic partnerships upcoming key catalyst for each therapy, along with their advantages, limitations, and recent developments. This section offers critical insights into the obesity treatment landscape, supporting market assessment, competitive analysis, and growth forecasting for the obesity therapeutics market.
Approved Therapies for Obesity
Orforglipron (FOUNDAYO): Eli Lilly
Orforglipron (FOUNDAYO) is an oral, once-daily GLP-1 receptor agonist developed by Eli Lilly and approved by the US FDA, for use in combination with a reduced-calorie diet and increased physical activity to reduce excess body weight and maintain long-term weight reduction in adults with obesity or adults with overweight and at least one weight-related comorbidity. Orforglipron is administered orally with or without food, with an approved maximum dose of 17.2 mg once daily, and represents a new oral GLP-1 treatment option for chronic weight management.
Obesity Pipeline Analysis
Enicepatide (CT-388): Roche/Carmot Therapeutics
Enicepatide (CT-388) is an investigational once-weekly subcutaneous dual GLP-1/GIP receptor agonist for obesity and associated comorbidities, including type 2 diabetes. It features biased signaling with minimal B-arrestin recruitment, supporting sustained receptor activity. CT-388 was designed to have potent activity on both the GLP-1 and GIP receptors but with minimal to no B-arrestin recruitment on either receptor. This biased signaling significantly minimizes receptor internalization and consequent desensitization, which is expected to lead to prolonged pharmacological activity.
Obesity Key Players, Market Leaders and Emerging Companies
And more
Obesity Drug Updates
The obesity market outlook remains highly positive, driven by the growing adoption of highly effective incretin-based therapies and continued pipeline innovation. Semaglutide (WEGOVY) and tirzepatide (ZEPBOUND) are expected to remain key market leaders, supported by substantial weight-loss efficacy and expanding indications. Established therapies such as orlistat (XENICAL), and phentermine/topiramate (QSYMIA) are likely to retain a role in specific patient populations. Meanwhile, emerging therapies could further intensify competition and expand treatment options, supporting sustained growth of the obesity market.
Drug Class/Insights into Leading Emerging Therapies in Obesity (2022-2036 Forecast)
The obesity treatment landscape includes small molecules, peptides, recombinant DNA therapies, monoclonal antibodies, GLP-1 receptor agonists, dual/multi-receptor incretin agonists, and combination therapies, with increasing emphasis on efficacy, tolerability, and convenient administration. Small molecules remain important due to their oral convenience and established mechanisms, while peptide and recombinant DNA-based therapies dominate the newer incretin landscape. Monoclonal antibodies and other biologic approaches represent additional emerging modalities, although their role in obesity remains comparatively limited.
Obesity Drug Uptake
This section focuses on the uptake rate of potential drugs expected to be launched in the market during the forecast period (2026-2036). The analysis covers the obesity drug's uptake, performance at peak, factors affecting performance during prime years of growth, patient uptake by therapy, and anticipated sales generated by each drug.
Following its US approval and launch, orforglipron (FOUNDAYO) is positioned for fast market uptake, with its once-daily oral formulation offering a potentially differentiated and more convenient alternative to other obesity therapies.
Detailed insights of emerging therapies' drug uptake is included in the report...
Market Access and Reimbursement of therapies in Obesity
The report further provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenario of therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.
As the obesity market transitions toward broader adoption and oral therapies, manufacturers are increasingly leveraging affordability programs to improve patient access. While Injectable WEGOVY continues to carry a US list price of approximately USD 1,349 per month, although commercial insurance and cash-pay programs can reduce patient costs to as low as USD 25 and USD 349 per month, respectively.
Lilly's ZEPBOUND is offered through its Self-Pay Journey Program at USD 299-449 per month depending on dose, despite list prices ranging from approximately USD 499 to USD 1,086 per month. Meanwhile, the newly launched oral WEGOVY and Lilly's oral GLP-1 therapy, orforglipron (FOUNDAYO), have entered the market with self-pay prices starting at USD 149 per month, with most higher-dose regimens priced between USD 299 and USD 349 per month, reflecting a broader industry push to improve accessibility as the obesity treatment landscape expands.
Reimbursement is a crucial factor that affects the drug's access to the market. Often, the decision to reimburse comes down to the price of the drug relative to the benefit it produces in treated patients. To reduce the healthcare burden of these high-cost therapies, many payment models are being considered by payers and other industry insiders.
NOTE: Further Details are provided in the final report.
Obesity Therapies Price Scenario & Trends
Pricing and analogue assessment of obesity therapies highlights evolving price dynamics structures. This section summarizes the cost of approved treatments, closest and most appropriate analogue selection for emerging therapies, and understanding of how pricing influences market access, adherence, and long-term uptake.
Pricing of Obesity Approved Drugs
Industry Experts and Physician Views for Obesity
To keep up with obesity market trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry Experts were contacted for insights on the obesity emerging therapies, evolving treatment landscape, patient adherence to conventional therapies, therapy switching trends, drug adoption and uptake, accessibility challenges, and epidemiology and real-world prescription patterns in obesity, including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.
DelveInsight's analysts connected with 10+ KOLs to gather insights at country level. Centers such as the Princeton Spine & Joint Center, University Hospital Giessen, and Saitama Medical University etc. were contacted.
Their opinion helps understand and validate current and emerging obesity therapies, highlight unmet medical needs, provide epidemiological context, and support strategic decisions for market access, therapy adoption, and pipeline prioritization in obesity.
Qualitative Analysis: SWOT and Attribute Analysis
We perform qualitative and market Intelligence analysis using various approaches, such as SWOT analysis and attribute analysis.
In the SWOT analysis of obesity, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provide attribute analysis analyzes emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.
The team of analysts analyzes promising emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. In efficacy, the trial's primary and secondary outcome measures are evaluated, whereas the therapies' safety is evaluated, wherein the acceptability, tolerability, and adverse events are majorly observed. In addition, the scoring is also based on the route of administration, order of entry, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.
Market Insights